Moderate exercise does not enhance the positive effect of estrogen on bone mineral density in postmenopausal women.

Heikkinen, J; Kurttila-Matero, E; Kyllönen, E; Vuori, J; Takala, T; Väänänen, H K · Calcif Tissue Int · 1991

prospective_cohort · Level II

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Abstract

We studied the effects of physical activity and two types of estrogen treatment in a prospective study in 78 healthy postmenopausal women. A control group and two treatment groups receiving estradiol valerate and medroxyprogesterone acetate in 1- or 3-month cycles were monitored for 1 year. Half of each group took part in an exercise program. Lumbar and femoral bone mineral density increased in both of the estrogen-treatment groups. Physical exercise with estrogen treatment did not result in further increases in bone mineral densities.

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