Performance of QuantiFERON-TB testing in a tuberculosis outbreak at a primary school.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 18346520.
- Also identified by DOI 10.1016/j.jpeds.2007.12.014.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
This study compared the effectiveness of the QuantiFERON-TB Gold (QFT) assay with the Mantoux tuberculin skin test to detect Mycobacterium tuberculosis infection in 29 children during a school outbreak of tuberculosis. Of the 21 children with M. tuberculosis infection, 11 had a radiograph suggestive of the infection. The QFT assay was positive in all 21 of the children, and the Mantoux test was negative at first testing in 2 children (1 of whom was the sentinel case). The findings demonstrate that the QFT test is extremely useful in accurately identifying infected and uninfected children, permitting rapid intervention.
Medical subject headings
- Disease Outbreaks
- Immunoassay
- Interferon-gamma
- Mycobacterium tuberculosis
- Tuberculin Test
- Tuberculosis, Pulmonary