Prolonged action of enoximone in renal failure.
case_report · Level V
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- Record sourced from PubMed, PMID 1835317.
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Abstract
Enoximone was administered on two separate occasions to a 37-year-old woman with renal failure secondary to thrombotic thrombocytopenic purpura. Plasma concentrations of enoximone and its principal metabolite, enoximone sulphoxide, were measured over a 9-day period. As renal function improved the rate of elimination of enoximone sulphoxide increased. The duration of effect of enoximone may be prolonged in patients with renal failure.
Medical subject headings
- Acute Kidney Injury
- Imidazoles
- Phosphodiesterase Inhibitors