Measuring noncalcified coronary atherosclerotic plaque using voxel analysis with MDCT angiography: phantom validation.

Sabir, Adeel; Yam, Chun-Shan; Yoshimura, Norihiko; Buros, Jacqueline L; De Grand, Alec M; Raptopoulos, Vassilios; Clouse, Melvin E · AJR Am J Roentgenol · 2008

basic_science · Level V

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Abstract

This purpose of this study was to evaluate the accuracy and reproducibility of a voxel analysis technique for measuring noncalcified plaque in the coronary arteries. Polyethylene phantoms representing noncalcified plaque were scanned in both MDCT and micro-CT scanners and inter- and intrareader variability of volume calculation was performed. Volume measurements by both MDCT and micro-CT were comparable to the true volume as measured by micrometry (< 3%, p = 0.05). There appears to be no significant difference (< 3%) between MDCT and micro-CT measurements.

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