SKNy worms and long life.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18358801.
- Also identified by DOI 10.1016/j.cell.2008.03.002.
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Abstract
Interactions between insulin signaling and stress-response pathways can markedly impact life span. In this issue, Tullet et al. (2008) demonstrate that the worm homolog of Nrf2, called SKN-1, a transcription factor that switches on expression of antioxidant genes, is an important component of such signaling interactions.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- DNA-Binding Proteins
- Gene Regulatory Networks
- Transcription Factors