Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors.

Christian, Nicolas; Lee, John A; Bol, Anne; De Bast, Marc; Gallez, Bernard; Grégoire, Vincent · Radiother Oncol · 2008

basic_science · Level V

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Abstract

Biological image-guided radiotherapy requires that PET accurately identifies biologically relevant sub-volumes within a tumor. In this framework, an immobilization device was developed to study multi-imaging (CT, micro-MRI, micro-PET, and autoradiography) registration of mouse tumors. The registration accuracy assessed by calculating the average minimal distance between two skew lines was in the order of 0.2-0.3 mm.

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