Stem cell epigenetics: is it all downhill from here?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18371328.
- Also identified by DOI 10.1016/j.stem.2007.05.016.
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Abstract
In this issue of Cell Stem Cell, Fasano et al. (2007) investigate the role of Bmi-1 in neural stem cells in vitro and in vivo. They find a progressively increasing requirement for Bmi-1 function in stem cells during development that, surprisingly, seems to involve regulation of the cell-cycle inhibitor p21.
Medical subject headings
- Epigenesis, Genetic
- Stem Cells