The missing niche for spermatogonial stem cells: do blood vessels point the way?

Shetty, Gunapala; Meistrich, Marvin L · Cell Stem Cell · 2007

review · Level V

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Abstract

Although spermatogonial stem cell niches have been defined in lower organisms, their definitive localization in mammalian seminiferous tubules has been elusive. In a recent Science paper, Yoshida et al. (2007) elegantly demonstrated a vascular and interstitial tissue-associated niche for undifferentiated spermatogonia in the mouse.

Medical subject headings