Sic transit gloria: farewell to the epidermal transit amplifying cell?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18371376.
- Also identified by DOI 10.1016/j.stem.2007.09.014.
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Abstract
For the past 30 years, the prevailing model of epidermal homeostasis has been that epidermal stem cells give rise to transit amplifying cells, which undergo a limited number of cell divisions before initiating terminal differentiation. Recent studies challenge the existence of a transit amplifying cell compartment and suggest a new paradigm for epidermal homeostasis.
Medical subject headings
- Epidermal Cells