New tools for genome modification in human embryonic stem cells.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18371400.
- Also identified by DOI 10.1016/j.stem.2007.11.004.
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Abstract
Two recent papers outline improvements in gene editing technology that may facilitate the analysis of signaling networks important for development. The systems developed by both Thyagarajan and coworkers (Thyagarajan et al., 2007) in Nature Biotechnology, and Lombardo and colleagues (Lombardo et al., 2007) in Stem Cells, have the potential to advance our understanding of human embryonic stem cells.
Medical subject headings
- DNA Mismatch Repair
- Embryonic Stem Cells
- Gene Targeting
- Gene Transfer Techniques
- Genome