Why myc? An unexpected ingredient in the stem cell cocktail.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18371417.
- Also identified by DOI 10.1016/j.stem.2007.12.004.
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Abstract
Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cells has identified a surprising new embryonic stem cell regulator, the myc proto-oncogene. Here the possible mechanisms by which myc controls self-renewal and pluripotency are discussed.
Medical subject headings
- Cell Differentiation
- Gene Expression Regulation, Developmental
- Proto-Oncogene Proteins c-myc
- Stem Cells