A new role for an old friend: NFAT and stem cell quiescence.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18371427.
- Also identified by DOI 10.1016/j.stem.2008.01.008 and PMC identifier 3839661.
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Abstract
NFAT proteins are calcium-regulated transcription factors that play a critical role during the timing and activation of many vertebrate tissues. A recent paper in Cell (Horsley et al., 2008) demonstrates a role of the calcineurin-NFAT-CDK4 pathway in maintaining hair follicle stem cell quiescence.
Medical subject headings
- Hair Follicle
- NFATC Transcription Factors
- Signal Transduction
- Stem Cells