Directing stem cell homing.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18371444.
- Also identified by DOI 10.1016/j.stem.2008.02.012.
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Abstract
Stem cell-based regeneration depends partly on the delivery of stem cells to the damaged area. Recently in Nature Medicine, Sackstein et al. (2008) report that ex vivo fucosylation of surface CD44 promoted efficient adhesive interactions of manipulated mesenchymal stem cells with marrow vasculature and subsequent homing to endosteal surfaces.
Medical subject headings
- Hyaluronan Receptors
- Mesenchymal Stem Cells
- Regeneration