Opioid withdrawal syndrome on switching from hydromorphone to alfentanil.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 18372384.
- Also identified by DOI 10.1177/0269216307085391.
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Abstract
Opioid switching is increasingly practiced. This patient did not tolerate morphine, oxycodone or hydromorphone due to opioid toxicity. Finally switch to alfentanil was performed. The patient developed classical opioid withdrawal symptoms and signs from discontinuation of the hydromorphone. Administration of small aliqouts of this drug reversed the symptoms. The existance of incomplete cross tolerance between hydromorphone and alfentanil is demonstrated.
Medical subject headings
- Alfentanil
- Analgesics, Opioid
- Hydromorphone
- Intractable Pain
- Sigmoid Neoplasms
- Substance Withdrawal Syndrome