Visualization of unfavorable interactions in protein folds.

Weichenberger, Christian X; Byzia, Piotr; Sippl, Manfred J · Bioinformatics · 2008

basic_science · Level V

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Abstract

Three dimensional structures of proteins contain errors which often originate from limitations of the experimental techniques employed. Such errors frequently result in unfavorable atomic interactions. Here we present a new web service, called Interaction Viewer, for the visualization and correction of such errors. We show how the Interaction Viewer is used in combination with the NQ-Flipper service to spot strained asparagine and glutamine rotamers and we emphasize the convenience of this service in correcting such errors. The web service is integrated with the NQ-Flipper service and accessible at http://flipper.services.came.sbg.ac.at

Medical subject headings