Supersized kidneys: Lessons from the preclinical obese kidney.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 18379527.
- Also identified by DOI 10.1038/ki.2008.42.
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Abstract
The worldwide prevalence of obesity continues to rise. Obesity has been shown to increase the risk of both the development and the progression of renal failure, even after correction for other comorbid conditions. The ability of nephrologists to intervene will require greater understanding of obesity's renal physiologic effects. Kidney biopsies and functional studies performed on morbidly obese patients without overt renal disease who presented for bariatric surgery have helped to elucidate the earliest obesity-related structural and functional responses.
Medical subject headings
- Kidney Glomerulus
- Obesity, Morbid