Eosinophilic granuloma of the ischium in an infant.

Abstract

This report presents an infant with a solitary eosinophilic granuloma (EG) in an unusual localization at an unusual age treated solely by vinblastine. A solitary EG of the right ischium was detected in a 17-month-old infant as confirmed by a computerized tomography-guided biopsy. He was treated with vinblastine, which was given 6 mg/m per week for a total of six doses. A complete cure was obtained as confirmed by a disease-free follow-up period of 5 years. Chemotherapy is an effective treatment option for a solitary EG in young children considering the risk of dissemination. Moreover, if the disease involves an area where surgery is considered difficult and morbid, or if it involves soft tissues, single-drug chemotherapy can be considered for treatment.