A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure.

Mroczek, W J; Burris, J F; Klein, J · Postgrad Med J · 1991

rct · Level II

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Abstract

The effects of amlodipine on ambulatory blood pressure were investigated in patients with mild-to-moderate hypertension. Ambulatory recordings showed that amlodipine maintained diastolic and systolic blood pressure below baseline levels for a full 24-h period without altering the normal circadian rhythm. No reflex tachycardia occurred and side effects were rare.

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