Complex I: a complex gateway to the powerhouse.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18396129.
- Also identified by DOI 10.1016/j.cmet.2008.03.011.
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Abstract
Complex I, the main entry point for electrons to the respiratory chain, is of critical importance for cellular energy homeostasis. In this issue of Cell Metabolism, Kruse and coworkers (2008) describe the first mouse knockout for a complex I structural subunit, thus advancing our understanding of complex I in disease.
Medical subject headings
- Electron Transport Complex I
- Mitochondrial Diseases
- NADH Dehydrogenase