When BAD is good for beta cells.
Level V
Where this comes from
- Record sourced from PubMed, PMID 18396130.
- Also identified by DOI 10.1016/j.cmet.2008.03.009.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
BAD, a proapoptotic member of the Bcl-2 family of proteins, is regulated by phosphorylation. A recent study (Danial et al., 2008) suggests a phosphorylation-state-dependent bifunctional role of BAD in the regulation of glucose-stimulated insulin secretion and beta cell mass.
Medical subject headings
- Insulin-Secreting Cells
- bcl-Associated Death Protein