Diabetes and cognitive decline: are steroids the missing link?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18396133.
- Also identified by DOI 10.1016/j.cmet.2008.03.012.
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Abstract
Although elevated cortisol levels may be found in diabetes, cortisol's role in diabetes-associated cognitive impairment is unclear. A recent study (Stranahan et al., 2008) shows that reducing glucocorticoid levels in rodent diabetes models prevents cognitive deficits and enhances neurogenesis and synaptic plasticity. The clinical relevance of these intriguing findings remains undetermined.
Medical subject headings
- Cognition Disorders
- Diabetes Complications
- Diabetes Mellitus
- Glucocorticoids