Illuminating the black box of reprogramming.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18397745.
- Also identified by DOI 10.1016/j.stem.2008.03.015.
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Abstract
Yamanaka and colleagues, in a Science article currently published online, have generated induced pluripotent stem (iPS) cells from liver and stomach cells, suggesting that transcription factor-induced reprogramming is not restricted to particular cell types (Aoi et al., 2008). These results also provide important insight into the mechanistic basis of reprogramming.
Medical subject headings
- Cell Nucleus
- Cellular Reprogramming
- Embryo, Mammalian
- Pluripotent Stem Cells
- Transcription Factors