Cancer: inappropriate expression of stem cell programs?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18397746.
- Also identified by DOI 10.1016/j.stem.2008.03.014.
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Abstract
Cancer stem cells (CSCs) are a subpopulation of cancer cells that possess characteristics, including self-renewal, associated with normal stem cells. In this issue of Cell Stem Cell, Wong et al. (2008) define a core embryonic stem cell (ESC)-like gene expression program that may be important for CSC function in multiple epithelial cancers.
Medical subject headings
- Adult Stem Cells
- Biomarkers, Tumor
- Embryonic Stem Cells
- Epithelium
- Neoplasms, Experimental
- Neoplastic Stem Cells
- Transcription, Genetic