EPO-KB: a searchable knowledge base of biomarker to protein links.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 18400772.
- Also identified by DOI 10.1093/bioinformatics/btn125 and PMC identifier 2567111.
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Abstract
The knowledge base EPO-KB (Empirical Proteomic Ontology Knowledge Base) is based on an OWL ontology that represents current knowledge linking mass-to-charge (m/z) ratios to proteins on multiple platforms including Matrix Assisted Laser/Desorption Ionization (MALDI) and Surface Enhanced Laser/Desorption Ionization (SELDI)--Time of Flight (TOF). At present, it contains information on m/z ratio to protein links that were extracted from 120 published research papers. It has a web interface that allows researchers to query and retrieve putative proteins that correspond to a user-specified m/z ratio. EPO-KB also allows automated entry of additional m/z ratio to protein links and is expandable to the addition of gene to protein and protein to disease links. http://www.dbmi.pitt.edu/EPO-KB
Medical subject headings
- Algorithms
- Artificial Intelligence
- Database Management Systems
- Databases, Protein
- Information Storage and Retrieval
- Pattern Recognition, Automated
- Proteins