The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation.
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- Record sourced from PubMed, PMID 18436575.
- Also identified by DOI 10.1093/bib/bbn016.
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Abstract
Since its beginning as a data collection more than 20 years ago, the TRANSFAC project underwent an evolution to become the basis for a complex platform for the description and analysis of gene regulatory events and networks. In the following, I describe what the original concepts were, what their present status is and how they may be expected to contribute to future system biology approaches.
Medical subject headings
- Chromosome Mapping
- Gene Expression Regulation
- Models, Biological
- Proteome
- Signal Transduction
- Systems Biology
- Transcription Factors