Risk of Guillain-Barré syndrome following serogroup C meningococcal conjugate vaccine in Quebec, Canada.

De Wals, Philippe; Deceuninck, Geneviève; Boucher, Renée-Myriam; Ouakki, Manale · Clin Infect Dis · 2008

retrospective_cohort · Level III

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Abstract

To assess the risk of Guillain-Barré syndrome (GBS) following administration of meningococcal serogroup C-CRM(197) conjugate vaccine, provincial immunization records were linked with hospital discharge records, and medical charts were reviewed. In the cohort of 1.9 million individuals (age, 2 months to 20 years), observed postvaccination frequencies of GBS were not higher than expected.

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