CD4+ T cell depletion in an untreated HIV type 1-infected human leukocyte antigen-B*5801-positive patient with an undetectable viral load.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 18444844.
- Also identified by DOI 10.1086/529387 and PMC identifier 2664682.
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Abstract
We report a case of a patient infected with human immunodeficiency virus type 1 (HIV-1) for 20 years who has experienced CD4(+) T cell depletion in spite of maintaining undetectable viral loads. Our data suggest that immune activation can cause CD4(+) T cell depletion even when HIV-1 replication appears to be controlled by host factors.
Medical subject headings
- CD4-Positive T-Lymphocytes
- HIV Infections
- HIV-1
- Lymphocyte Depletion
- Viral Load