Clinical differences between bipolar and unipolar depression.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 18450667.
- Also identified by DOI 10.1192/bjp.bp.107.045294.
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Abstract
It is commonly -- but wrongly -- assumed that there are no important differences between the clinical presentations of major depressive disorder and bipolar depression. Here we compare clinical course variables and depressive symptom profiles in a large sample of individuals with major depressive disorder (n=593) and bipolar disorder (n=443). Clinical characteristics associated with a bipolar course included the presence of psychosis, diurnal mood variation and hypersomnia during depressive episodes, and a greater number of shorter depressive episodes. Such features should alert a clinician to a possible bipolar course. This is important because optimal management is not the same for bipolar and unipolar depression.
Medical subject headings
- Bipolar Disorder
- Depressive Disorder