DAnTE: a statistical tool for quantitative analysis of -omics data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18453552.
- Also identified by DOI 10.1093/bioinformatics/btn217 and PMC identifier 2692489.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Data Analysis Tool Extension (DAnTE) is a statistical tool designed to address challenges associated with quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide-to-protein rollup methods, an extensive array of plotting functions and a comprehensive hypothesis-testing scheme that can handle unbalanced data and random effects. The graphical user interface (GUI) is designed to be very intuitive and user friendly. DAnTE may be downloaded free of charge at http://omics.pnl.gov/software/. An example dataset with instructions on how to perform a series of analysis steps is available at http://omics.pnl.gov/software/
Medical subject headings
- Algorithms
- Data Interpretation, Statistical
- Databases, Protein
- Peptide Mapping
- Proteome
- Proteomics
- Software