Epigenome sequencing comes of age.

Zhu, Jian-Kang · Cell · 2008

basic_science · Level V

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Abstract

Epigenetic states are responsive to developmental and environmental signals, and as a consequence a eukaryotic cell can have many different epigenomes. In this issue of Cell, Lister et al. (2008) present the floral epigenome of Arabidopsis using next-generation sequencing technology to analyze both DNA methylation at single-base resolution and the expression of small RNAs.

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