CaMKII: new tricks for an old dog.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18455979.
- Also identified by DOI 10.1016/j.cell.2008.04.018 and PMC identifier 2655315.
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Abstract
Calcium/calmodulin-dependent protein kinase II (CaMKII) is a pivotal signaling molecule in both the brain and the heart. In this issue of Cell, Erickson et al. (2008) demonstrate a mechanism for CaMKII activation by reactive oxygen species that provides a direct link between kinase activation and cardiac dysfunction.
Medical subject headings
- Calcium-Calmodulin-Dependent Protein Kinase Type 2
- Heart Diseases
- Myocytes, Cardiac