What's the point of the type III secretion system needle?
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- Record sourced from PubMed, PMID 18458349.
- Also identified by DOI 10.1073/pnas.0708344105 and PMC identifier 2373345.
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Abstract
Recent work by several groups has significantly expanded our knowledge of the structure, regulation of assembly, and function of components of the extracellular portion of the type III secretion system (T3SS) of Gram-negative bacteria. This perspective presents a structure-informed analysis of functional data and discusses three nonmutually exclusive models of how a key aspect of T3SS biology, the sensing of host cells, may be performed.
Medical subject headings
- Bacterial Proteins