Manipulating midbrain stem cell self-renewal.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18462687.
- Also identified by DOI 10.1016/j.stem.2008.04.007 and PMC identifier 2601722.
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Abstract
In this issue of Cell Stem Cell, Falk and colleagues (Falk et al., 2008) demonstrate that differential responsiveness to TGF-beta signaling selectively modulates self-renewal of dorsal midbrain stem cells. This observation may lead to strategies for expanding specific neural stem cell subtypes.
Medical subject headings
- Gene Expression Regulation, Developmental
- Neurons
- Signal Transduction
- Stem Cells
- Tectum Mesencephali
- Transforming Growth Factor beta