Complete remission in refractory anaplastic adult Wilms' tumor treated with cisplatin and etoposide.

Sparano, J A; Beckwith, J B; Mitsudo, S; Wiernik, P H · Cancer · 1991

case_report · Level V

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Abstract

A 61-year-old woman underwent a left radical nephrectomy for Stage II anaplastic Wilm's tumor. She received no adjuvant therapy. One year later computerized tomography (CT) of the abdomen revealed a mass in the left renal fossa and retroperitoneal adenopathy. A CT-guided needle biopsy was nondiagnostic. The patient had progressive disease after treatment with dactinomycin, doxorubicin, and vincristine, but achieved a complete response after treatment with cisplatin and etoposide. The therapy of Wilms' tumor in adults is discussed.

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