Large-cell anaplastic (Ki-1-positive) lymphoma complicated by disseminated intravascular coagulation.
case_report · Level V
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Abstract
Large-cell anaplastic lymphoma (Ki-1-positive lymphoma) was first described as a type of large-cell lymphoma that has morphologic, enzymatic, and immunologic similarities to malignant histiocytosis. To date, an association between Ki-1-positive lymphoma and disseminated intravascular coagulation has not been described, but cases of malignant histiocytosis with disseminated intravascular coagulation have been reported. We report a case of anaplastic, Ki-1-positive, large-cell lymphoma complicated by clinical and laboratory evidence of disseminated intravascular coagulation with histologic evidence of vascular invasion and fibrin thrombi.
Medical subject headings
- Antigens, CD
- Antigens, Differentiation
- Antigens, Neoplasm
- Disseminated Intravascular Coagulation
- Lymphoma, Large B-Cell, Diffuse