Another niche for Notch.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18480851.
- Also identified by DOI 10.1038/ki.2008.39.
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Abstract
The Notch signaling pathway patterns the developing nephron along the proximal-distal axis during renal development. In an adult acute tubular necrosis model, Kobayashi et al. now show expression of many Notch components and the activation of Notch target genes, suggesting a critical function for Notch in regenerating proximal tubules.
Medical subject headings
- Kidney Tubules
- Receptors, Notch
- Regeneration