Giving space to cell signaling.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18485861.
- Also identified by DOI 10.1016/j.cell.2008.04.033.
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Abstract
Spatial separation of component enzymes in a pathway creates microdomains and gradients of signaling activities. Imaging techniques and computational modeling help us to understand the complex relationships between signaling and spatial information. In this issue, Neves et al. (2008) report how the propagation of spatial information is controlled by the shape of hippocampal neurons and feedback and feed-forward motifs of the beta-adrenergic receptor signaling pathway.
Medical subject headings
- Neurons
- Signal Transduction