Twin ushers guide pili across the bacterial outer membrane.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18485865.
- Also identified by DOI 10.1016/j.cell.2008.04.032.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The chaperone/usher pathway is responsible for the assembly of adhesive pili on the surface of gram-negative pathogenic bacteria. In this issue, Remaut et al. (2008) present the crystal structure of the PapC usher translocation domain and images of the FimD usher bound to a pilus translocation intermediate. These new structures provide the first detailed view of a translocase in action.
Medical subject headings
- Biosynthetic Pathways
- Escherichia coli
- Fimbriae, Bacterial