Poised RNA polymerase II gives pause for thought.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18485867.
- Also identified by DOI 10.1016/j.cell.2008.04.027.
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Abstract
Transcription by RNA polymerase II (Pol II) is thought to be predominantly regulated by recruitment of Pol II to promoters. Recent genome-wide analyses demonstrate that many genes are in fact regulated after recruitment of Pol II, by mechanisms such as pausing of Pol II proximal to promoters.
Medical subject headings
- Gene Expression Regulation
- RNA Polymerase II
- Transcription, Genetic