Swelfe: a detector of internal repeats in sequences and structures.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18487242.
- Also identified by DOI 10.1093/bioinformatics/btn234 and PMC identifier 2718673.
- Licence recorded as CC BY-NC.
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Abstract
Intragenic duplications of genetic material have important biological roles because of their protein sequence and structural consequences. We developed Swelfe to find internal repeats at three levels. Swelfe quickly identifies statistically significant internal repeats in DNA and amino acid sequences and in 3D structures using dynamic programming. The associated web server also shows the relationships between repeats at each level and facilitates visualization of the results. http://bioserv.rpbs.jussieu.fr/swelfe. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Algorithms
- Internet
- Repetitive Sequences, Nucleic Acid
- Sequence Alignment
- Sequence Analysis
- Software