Granular parakeratosis in a patient treated with liposomal doxorubicin for ovarian carcinoma.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 18489055.
- Also identified by DOI 10.1016/j.jaad.2007.05.031.
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Abstract
Granular parakeratosis is a rare benign dermatosis caused by an acquired disorder of keratinization that usually manifests with reddish-brown keratotic papules and plaques in intertriginous areas. It has specific histologic features but its pathogenesis remains unclear. Its frequency is probably underestimated because the condition is usually misdiagnosed as simple intertrigo. We report herein a new case of granular parakeratosis in a woman treated with liposomal doxorubicin for ovarian carcinoma that showed complete remission after discontinuation of chemotherapy. The relationship between granular parakeratosis and chemotherapy is discussed.
Medical subject headings
- Antibiotics, Antineoplastic
- Doxorubicin
- Ovarian Neoplasms
- Parakeratosis
- Polyethylene Glycols