Hippocampal volume and 2-year outcome in depression.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 18515903.
- Also identified by DOI 10.1192/bjp.bp.107.040378.
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Abstract
Although the hippocampus has been found to be smaller in people with depression, the clinical relevance of this is unclear. We investigated hippocampal volume (using high-resolution magnetic resonance imaging) and 2-year outcome in 57 patients with major depression. The left and right hippocampal volumes of patients with a depression relapse were significantly smaller than those of healthy controls. Our results support the hypothesis that the hippocampus is crucial in the outcome of depression.
Medical subject headings
- Major Depressive Disorder
- Hippocampus