Epithelial-mesenchymal transition and the stem cell phenotype.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18522839.
- Also identified by DOI 10.1016/j.stem.2008.05.007.
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Abstract
Epithelial-mesenchymal transition (EMT) is a developmental process in which epithelial cells acquire the motile, migratory properties of mesenchymal cells. In a recent issue of Cell, Mani et al. (2008) show that induction of EMT stimulates cultured breast cells to adopt characteristics of stem cells.
Medical subject headings
- Cell Transdifferentiation
- Epithelial Cells
- Mesenchymal Stem Cells
- Neoplastic Stem Cells