Home is where the heart is: via the FROUNT.

Zannettino, Andrew C W; Psaltis, Peter J; Gronthos, Stan · Cell Stem Cell · 2008

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Belema-Bedada et al. (2008) describe a novel mechanism by which bone marrow-derived adult mesenchymal stem cells migrate to sites of damaged heart tissue. This process is dependent on the intracellular adaptor molecule FROUNT, which interacts with the chemokine receptor CCR2.

Medical subject headings