Rehabilitation of a contract killer: caspase-3 directs stem cell differentiation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18522841.
- Also identified by DOI 10.1016/j.stem.2008.05.013.
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Abstract
Activation of caspase-3 is generally acknowledged as a penultimate step in apoptotic cell death pathways. Two studies in this issue of Cell Stem Cell (Fujita et al., 2008; Janzen et al., 2008) provide compelling data to demonstrate that caspase-3 is also a conserved inductive cue for stem cell differentiation.
Medical subject headings
- Caspase 3
- Cell Differentiation
- Embryonic Stem Cells
- Hematopoietic Stem Cells