Portable compression device and low-molecular-weight heparin compared with low-molecular-weight heparin for thromboprophylaxis after total joint arthroplasty.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 18534421.
- Also identified by DOI 10.1016/j.arth.2007.11.006.
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Abstract
This preliminary prospective study to determine the rate of deep venous thrombosis (DVT) examined 277 patients undergoing total knee or total hip arthroplasty (TKA or THA) who were randomized to use a portable, continuous enhanced circulation therapy (CECT) compression device and low-molecular-weight heparin (LMWH) or to receive LMWH alone. Patients were screened for DVT using duplex ultrasound at hospital discharge and followed clinically for 3 months. In TKA, 5 DVTs (6.6%) occurred in the CECT + LMWH group compared with one pulmonary embolism and 14 DVTs (19.5%) in the LMWH group (P = .018). In THA, 1 DVT (1.5%) occurred in the CECT + LMWH group and 2 DVTs (3.4%) occurred in the LMWH group. This preliminary study demonstrated significant reduction in rate of DVT after TKA when the CECT device was combined with LMWH.
Medical subject headings
- Anticoagulants
- Arthroplasty, Replacement, Hip
- Arthroplasty, Replacement, Knee
- Heparin, Low-Molecular-Weight
- Intermittent Pneumatic Compression Devices
- Venous Thrombosis
Anatomy
- knee
- hip