Low positive predictive value of a nucleic acid amplification test for nongenital Neisseria gonorrhoeae infection in homosexual men.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 18549310.
- Also identified by DOI 10.1086/589299.
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Abstract
The diagnosis of nongenital Neisseria gonorrhoeae infection by the Becton Dickinson ProbeTec ET Chlamydia trachomatis and N. gonorrhoeae Amplified DNA assay had low positive predictive value among an Australian community-based sample of homosexual men. Only 30.4% of oropharyngeal samples and 73.7% of anorectal samples were positive for N. gonorrhoeae by the porA assay. The accuracy of nucleic acid amplification tests in this context is compromised without supplemental testing.
Medical subject headings
- Anal Canal
- Gonorrhea
- Homosexuality, Male
- Molecular Diagnostic Techniques
- Neisseria gonorrhoeae
- Nucleic Acid Amplification Techniques
- Oropharynx