Swapping nucleotides, tuning Hsp70.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18555768.
- Also identified by DOI 10.1016/j.cell.2008.05.036 and PMC identifier 4445657.
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Abstract
Molecular chaperones such as heat shock protein 70 (Hsp70) are crucial for protein folding. Crystal structures of Hsp70 in a complex with the nucleotide exchange factor (NEF) Hsp110 reported in this issue of Cell (Polier et al., 2008) and in Molecular Cell (Schuermann et al., 2008) provide new insights into how NEF action specifies Hsp70 cellular function.
Medical subject headings
- HSP70 Heat-Shock Proteins