Rewiring bacteria, two components at a time.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18555769.
- Also identified by DOI 10.1016/j.cell.2008.05.035.
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Abstract
In this issue, Skerker et al. (2008) present a rational method for rewiring the protein-protein interactions and output responses of prokaryotic two-component signal transduction systems. This work has important implications for understanding the specificity of protein interactions and for designing protein-based synthetic signaling cascades.
Medical subject headings
- Bacteria
- Bacterial Proteins
- Protein Engineering
- Signal Transduction