Ritonavir-boosted atazanavir, methadone, and ventricular tachycardia: 2 case reports.
case_report · Level V
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- Record sourced from PubMed, PMID 18558878.
- Also identified by DOI 10.1086/589869.
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Abstract
We describe 2 cases of symptomatic ventricular tachycardia associated with prolonged QT interval. Both patients were infected with the human immunodeficiency virus and were receiving treatment with ritonavir-boosted atazanavir and methadone. Discontinuation of atazanavir in both cases resulted in a reduction in the QT interval and cessation of arrhythmia. We concluded that atazanavir contributed to prolonged corrected QT interval and subsequent ventricular tachycardia.
Medical subject headings
- HIV Infections
- HIV Protease Inhibitors
- Oligopeptides
- Pyridines
- Tachycardia, Ventricular